Baked High-Protein Pepperoni Stromboli

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This hearty Italian-American stromboli wraps seasoned lean ground beef, savory pepperoni, and a blend of mozzarella and Parmesan cheeses inside golden pizza dough. Baked until perfectly crisp and melty, each generous slice delivers satisfying protein and rich flavors. The dough emerges from the oven with a beautiful golden sheen from the egg wash, while diagonal steam vents ensure even cooking throughout. Serve warm with extra pizza sauce for dipping to experience the full depth of flavors.

Updated on Mon, 09 Feb 2026 14:26:00 GMT
Freshly baked Baked High-Protein Pepperoni Stromboli rests on a cutting board, showcasing melted mozzarella and savory pepperoni slices inside. Save
Freshly baked Baked High-Protein Pepperoni Stromboli rests on a cutting board, showcasing melted mozzarella and savory pepperoni slices inside. | berrycottage.com

My kitchen got unexpectedly quiet one Tuesday when my teenage nephew showed up hungry after soccer practice, and I realized I had exactly what I needed to make something that would actually impress him. There's something about rolling up a stromboli that feels both impressive and deceptively simple, like you're doing something fancy when really you're just folding together the best parts of pizza night. This high-protein version came together almost by accident when I started adding extra cheese and pepperoni to stretch the filling further, and somehow it became the thing everyone started requesting. The golden, crispy exterior hiding that savory beef and cheese center feels like the kind of meal that bridges the gap between lunch and dinner, between casual and special.

I made this for my brother's game day gathering last fall, and it disappeared so quickly that people were actually disappointed there wasn't more. Watching folks bite into that first slice and see the layers of beef, cheese, and pepperoni tumble out was weirdly satisfying, like I'd pulled off some culinary magic trick. That moment convinced me this recipe deserved a permanent spot in my rotation, not just as a one-off novelty.

Ingredients

  • Refrigerated pizza dough (1 pound): The foundation of everything, and using the refrigerated kind saves you the hassle of dealing with yeast and rising times while still delivering actual flavor.
  • Lean ground beef (1/2 pound): Browning it first ensures it's cooked through and allows you to drain off excess fat, keeping the filling from getting greasy.
  • Salt, black pepper, dried oregano, and garlic powder: This simple seasoning blend is all you need to make the beef taste like it belongs in an Italian-American kitchen, not overdone or muddled.
  • Shredded mozzarella cheese (1 cup): This melts into those perfect stretchy strands, and the shredded variety distributes more evenly than blocks.
  • Grated Parmesan cheese (1/2 cup): The sharpness cuts through the richness and adds a salty depth that makes people ask what that amazing flavor is.
  • Sliced pepperoni (3 ounces): Pre-sliced saves time and the little cups curl up slightly in the oven, concentrating their peppery flavor throughout the roll.
  • Pizza sauce (1/4 cup plus extra): Use your favorite brand or homemade, but don't skimp on it—this is what keeps the filling from tasting dry.
  • Egg and olive oil for brushing: The egg gives you that restaurant-style golden sheen while the oil adds subtle richness and helps it crisp up beautifully.

Instructions

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Heat your oven and prepare:
Set your oven to 400°F and line a baking sheet with parchment paper so nothing sticks and cleanup becomes almost painless. This gives your oven time to reach full temperature while you work on the filling.
Brown the beef filling:
Cook the ground beef in a skillet over medium heat with all those seasonings, breaking it apart as it cooks until there's no pink left. Once it's done, drain off any excess fat and let it cool slightly so you're not cooking the cheese the moment you add it.
Roll out your dough canvas:
On a floured surface, stretch and roll the pizza dough into a rectangle about 12 by 16 inches—it doesn't need to be perfect, just roughly rectangular. A light dusting of flour under and over prevents sticking without making the dough tough.
Spread the sauce foundation:
Distribute the pizza sauce evenly across the dough, leaving about an inch around the edges so you have something to seal. This border is your secret to keeping the filling contained and the seam from bursting open in the oven.
Layer your filling strategically:
Spread the cooked beef across the sauce, then scatter mozzarella and Parmesan evenly, and finish with the pepperoni slices. The order matters because the cheese sort of locks everything in place as it melts.
Roll it into a log:
Starting from one long edge, roll the dough tightly toward you, using your hands to keep the tension even. As you reach the end, pinch that seam firmly and fold the ends under, sealing everything shut like you're wrapping a present.
Position for baking:
Transfer your stromboli to the baking sheet with the seam facing down so it stays sealed and gets that perfect golden bottom. The parchment paper prevents any sticking drama while baking.
Apply the golden finish:
Brush beaten egg all over the top surface and drizzle with olive oil for that crispy, glossy exterior that looks like it came from a real bakery. This step takes thirty seconds but makes an obvious difference.
Vent with intention:
Using a sharp knife, make several diagonal slits across the top to let steam escape during baking and prevent the dough from bursting. These slits also look intentional and professional, not like an accident.
Bake until golden:
Slide it into your preheated oven for 25 to 30 minutes until the top is deep golden brown and the whole kitchen smells incredible. You'll know it's done when tapping the bottom produces a hollow sound.
Rest before slicing:
Let the stromboli cool for 5 to 10 minutes after removing it from the oven so the filling sets slightly and doesn't spill everywhere. This patience pays off immediately when you make that first slice and everything stays intact.
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There's something genuinely comforting about pulling a stromboli out of the oven and knowing you've created something substantial enough to actually satisfy people. It became the thing my family requests now instead of asking me to order pizza.

Why the High-Protein Angle Works

Building this around lean ground beef and doubled cheese wasn't just about trendy macros—it was about creating something that actually stays with you through an afternoon instead of leaving you hungry an hour later. The protein in the beef, combined with the cheese, creates a filling that works as a legitimate lunch or dinner, not just a snack you'll supplement with other things. I started making it this way when my gym-focused friends came over, and they were genuinely surprised that something tasting this good could actually be high in protein.

Making It Work for Your Preferences

Swapping ground turkey or chicken for the beef works beautifully if you want to lighten things up, though the cooking time stays exactly the same and the final result feels just as satisfying. I've also added sautéed bell peppers or onions between the meat and cheese layers when I want to sneak in some vegetables, and nobody even notices they're eating something slightly healthier. The beauty of this formula is that it's flexible enough to adapt without losing what makes it special.

Storage and Reheating Like a Pro

Leftover stromboli (if there even is any) reheats beautifully wrapped loosely in foil at 350°F for about ten minutes, which brings back that fresh-from-the-oven quality without drying it out. Refrigerate it in an airtight container for up to three days, and it makes an unexpectedly great cold lunch the next day if you're not in the mood to reheat. This is honestly the kind of make-ahead meal that makes weeknight dinners feel less like a scramble.

  • Wrapping leftovers in foil while reheating prevents the outside from getting too crispy while the inside warms through.
  • Eating it cold straight from the fridge is oddly satisfying on a lazy day and tastes completely different from the warm version.
  • Freezing individual slices after cooling lets you reheat single portions whenever the craving hits, which is genuinely convenient.
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Sliced wedges of Baked High-Protein Pepperoni Stromboli reveal layers of lean ground beef and gooey cheese, perfect for dipping in pizza sauce. Save
Sliced wedges of Baked High-Protein Pepperoni Stromboli reveal layers of lean ground beef and gooey cheese, perfect for dipping in pizza sauce. | berrycottage.com

This stromboli became the meal that proved to me that cooking something impressive doesn't require hours of fussing or ingredients you can't find at any grocery store. It's the kind of dish that makes people happy and full, which is really the whole point.

Recipe FAQ

What makes this stromboli high-protein?

The combination of lean ground beef, pepperoni, mozzarella, and Parmesan cheese provides 26 grams of protein per serving, making it a substantial protein-rich meal.

Can I prepare this ahead of time?

Yes, you can assemble the stromboli, wrap it tightly in plastic, and refrigerate for up to 24 hours before baking. Add a few extra minutes to the baking time if baking cold from the refrigerator.

How do I prevent the dough from getting soggy?

Drain the cooked beef thoroughly to remove excess fat, and leave a 1-inch border around the dough edges when layering ingredients. The steam vents on top also help moisture escape during baking.

What can I serve with stromboli?

Serve with warm pizza sauce for dipping, a simple green salad with vinaigrette, or roasted vegetables. Garlic bread or breadsticks also complement the meal well.

Can I freeze leftover stromboli?

Wrap cooled slices individually in plastic wrap and freeze for up to 3 months. Reheat in a 350°F oven for 10-15 minutes or until heated through and crispy.

Why is resting important before slicing?

Letting the stromboli rest for 5-10 minutes allows the cheese to set slightly, preventing the filling from oozing out when you cut it and ensuring cleaner slices.

Baked High-Protein Pepperoni Stromboli

Hearty stromboli rolled with seasoned beef, pepperoni, and three cheeses in golden pizza dough.

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Prep duration
25 min
Cook duration
30 min
Complete duration
55 min
Created by Lily Anderson


Complexity Medium

Heritage Italian-American

Output 6 Portions

Dietary considerations None specified

Components

Dough

01 1 pound refrigerated pizza dough

Filling

01 1/2 pound lean ground beef
02 1/2 teaspoon salt
03 1/2 teaspoon black pepper
04 1/2 teaspoon dried oregano
05 1/2 teaspoon garlic powder
06 1 cup shredded mozzarella cheese
07 1/2 cup grated Parmesan cheese
08 3 ounces sliced pepperoni
09 1/4 cup pizza sauce, plus extra for serving
10 1 tablespoon chopped fresh parsley

For Brushing

01 1 large egg, beaten
02 1 tablespoon olive oil

Directions

Direction 01

Prepare oven and baking surface: Preheat oven to 400°F. Line a baking sheet with parchment paper.

Direction 02

Brown the beef: In a skillet over medium heat, cook the ground beef with salt, pepper, oregano, and garlic powder until fully browned. Drain excess fat and allow to cool slightly.

Direction 03

Roll out dough: On a floured surface, roll out the pizza dough into a large rectangle approximately 12 by 16 inches.

Direction 04

Apply sauce base: Spread the pizza sauce evenly over the dough, leaving a 1-inch border along all edges.

Direction 05

Layer filling ingredients: Evenly distribute the cooked beef, mozzarella, Parmesan, and pepperoni over the sauce in layers.

Direction 06

Roll and seal: Starting from one long edge, tightly roll up the dough into a log, pinching the seam and ends securely to seal.

Direction 07

Transfer to baking sheet: Place the stromboli on the prepared baking sheet with the seam side facing down.

Direction 08

Apply egg wash and oil: Brush the top with beaten egg and drizzle with olive oil to achieve shine and crispness.

Direction 09

Vent the stromboli: Using a sharp knife, make several diagonal slits across the top to allow steam to escape during baking.

Direction 10

Bake until golden: Bake for 25 to 30 minutes until the exterior is golden brown and the filling is cooked through.

Direction 11

Rest and serve: Allow the stromboli to cool for 5 to 10 minutes before slicing. Garnish with parsley if desired. Serve warm with extra pizza sauce for dipping.

Necessary tools

  • Skillet
  • Baking sheet
  • Parchment paper
  • Rolling pin
  • Sharp knife
  • Pastry brush

Allergy information

Review each ingredient for potential allergens and seek professional medical advice if you have concerns.
  • Contains wheat gluten
  • Contains milk
  • Contains egg
  • Pepperoni may contain soy and other allergens; verify labels if sensitive

Nutritional information (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 410
  • Fats: 22 g
  • Carbohydrates: 29 g
  • Proteins: 26 g